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VETSIPZONE GROUP INJECTION

Composition:

VET SIPZONE - S 4500^Each Vial Contains:^Sterile Cefoperazone Sodium IP equivalent to Cefoperazone (anhydrous) 3000 mg^Sterile Sulbactam Sodium USP equivalent to anhydrous Sulbactam 1500 mg^Sterile water for injections IP 25 ml

Dosage and administration:

Large animals 4 to 7 mg/kg body weight by IM or IV for 3 to 5 days (once a day)^Small animals 5 to 10 mg/kg body weight IM or IV for 3 to 5 days.

Indications:

Respiratory tract infections (upper and lower), Urinary tract infections (upper and lower), Peritonitis, cholecystitis, cholangitis, and other intra-abdominal infections, Septicaemia, Meningitis, Skin and soft tissue infections, Bone and joint infection, Pelvic inflammatory disease, endometritis, gonorrhea, and other infections of the genital tract

Mode of action:

Cefoperazone is the third generation cephalosporin antibacterial component. It is active against a wide range of gram-positive and gram-negative bacteria, including Enterobacteriaceae and Pseudomonas species. VETSIPZONE-S inhibits the bacterial cell wall synthesis and beta-lactamase. VETSIPZONE-S is available as a dry powder for reconstitution in a 1:2 ratio, which acts against sensitive organisms during the stage of active multiplication by inhibiting the biosynthesis of cell wall mucopeptide.

Spectrum of activity:

Gram positive Organisms : Staphylococcus aureus, penicillinase and non-penicillinase-producing strains, Streptococcus pneumonia, Streptococcus pyogenes (Group A beta-hemolytic streptococci) Streptococcusagalactiae (Group B beta-hemolytic streptococci) Most other strains of betahaemolytic streptococci, Many strains of Streptococcus faecalis^Gram negative Organisms : Escherichia coli, Klebsiella species ,Enterobacter species, Citrobacter species, Haemophilus influenzae Proteus mirabilis Proteus vulgaris, Morganella morganii (formerly Proteus morganii), Providencia rettgeri (formerly Proteus rettgeri), Providencia species, Serratia species (including S. marcescens) Salmonella and Shigella species, Pseudomonas aeruginosa and some other Pseudomonas species^Acinetobacter, Neisseria gonorrhea, Neisseria meningitides Bordetella pertussis, Yersinia enterocolitica^Anaerobic Organisms : Gram-negative bacilli (including Bacteroides fragilis, other Bacteroides species, and Fusobacterium species).